With Perfect Hotkey, you can easily create a hotkey for opening your favorite folder.
1. Run Perfect Hotkey program, Right-click the tray icon then select New Hotkey menu command.
2. Click on the + button to create actions for the hotkey.
3. Select Open Folder from the action list.
4. Specify the folder you want to open with the hotkey.
5. Click OK to save the changes and complete the process.
Now, whenever you press your hotkey (for example: Ctrl-Shift-O), even when using another program, your Client Files folder will magically appear.